Overview of Commercial Instruments


By the year 2004 the first commercial solutions for MALDI mass spectrometric imaging were introduced to the market. This list of instruments is continuously updated with information from manufacturers and users. Please provide missing parameters or corrections.

Actual Instruments

Instrument Company Type Laser Mass Range Resolution
(st*1, la*2)
Software Data Format
5800 MALDI TOF/TOF™ Analyzer AB Sciex TOF-TOF Nd-YAG
1000 Hz
full 1 µm
50 µm
4800 Img, TissueView Analyze
4800 Plus MALDI TOF/TOF™ Analyzer AB Sciex TOF-TOF Nd-YAG
200 Hz
full 1 µm
50 µm
4800 Img, TissueView Analyze
ultrafleXtreme Bruker TOF-TOF smartbeam-II
1000 Hz
full 5 µm
10 µm
flexImaging, CreateTarget, AnalyzeThis!, BioMap Xmass,
XML
Solarix MI Bruker hybrid FTMS smartbeam-II
1 kHz
100 – 10 kDa 5 µm
20 µm
flexImaging, BioMap Xmass,
XML
JMS-S3000 SpiralTOF™ JEOL TOF-TOF Nd:YLF 250Hz
(opt. 1kHz)
to 500 kDa (linear)
to 30kDa (spiral)
10 µm
30 µm
msTornado, BioMap imzML
AXIMA QIT™ Shimadzu ion trap TOF N2 to 20 kDa 10 µm
100 µm
Axima2Analyze Analyze
AXIMA Assurance Shimadzu TOF N2
50 Hz
to 500 kDa (linear) 10 µm
100 µm
Axima2Analyze Analyze
AXIMA Confidence
AXIMA Performance
Shimadzu TOF
TOF-TOF
N2
50 Hz
to 500 kDa (linear)
to 80 kDa (reflectron)
10 µm
100 µm
Axima2Analyze Analyze
MALDI LTQ XL  Thermo Fisher Scientific  ion trap N2
60 Hz
50 – 4000 Da 1 µm
60 µm
LTQ Tune, ImageQuest RAW, imzML
MALDI LTQ Orbitrap Discovery  Thermo Fisher Scientific ion trap –
Orbitrap hybrid
N2
60 Hz
50 – 4000 Da 1 µm
60 µm
LTQ Tune, ImageQuest RAW. imzML
MALDI LTQ Orbitrap XL  Thermo Fisher Scientific ion trap –
Orbitrap hybrid
N2
60 Hz
50 – 4000 Da 1 µm
60 µm
LTQ Tune, ImageQuest RAW, imzML
MALDI SYNAPT G2 HDMS Waters Q-IMS-oaTOF Nd-YAG
1 kHz
to 40 kDa 3.5 µm
60/200 µm
MassLynx, BioMap XML
MALDI SYNAPT G2 MS Waters Q-TWave-oaTOF Nd-YAG
1 kHz
to 40 kDa 3.5 µm
60/200 µm
MassLynx, BioMap XML

*1 mechanical resolution limited by sample stage positioning or software
*2 approx. laser beam diameter on sample

Past Instruments

Instrument Company Type Laser Mass Range Resolution
(st*1, la*2)
Software Data Format
QSTAR® Elite System AB Sciex QqTOF Nd-YAG
1 kHz
40 to
40 kDa
30 µm
150 µm
oMALDI Server 5.1, TissueView Wiff, Analyze, imzML
QSTAR® Pulsar i System Applied Biosystems/
MDS Sciex
QqTOF Nd-YAG
1 kHz
40 to
40 kDa
30 µm
150 µm
oMALDI Server 5.1, TissueView Wiff, Analyze
QSTAR® XL System Applied Biosystems/
MDS Sciex
QqTOF Nd-YAG
1 kHz
40 to
40 kDa
30 µm
150 µm
oMALDI Server 5.1, TissueView Wiff, Analyze
4700 Proteomics Analyzer Applied Biosystems/
MDS Sciex
TOF-TOF Nd-YAG
200 Hz
full 1 µm
50 µm
4700 Img, TissueView Analyze
Voyager DE™ STR Workstation Applied Biosystems/
MDS Sciex
TOF N2
20 Hz
full 1.6 µm
100 µm
MMSIT, BioMap Analyze
Voyager DE™ PRO Workstation Applied Biosystems/
MDS Sciex
TOF N2
20 Hz
full 1.6 µm
100 µm
MMSIT, BioMap Analyze
autoflex III ,
ultraflex III
Bruker TOF-TOF smartbeam
200 Hz
full 5 µm
10 µm
(ultraflex 30 µm)
flexImaging, CreateTarget, AnalyzeThis!, BioMap Analyze
MALDI Q-Tof Premier Waters Qq-oaTOF Nd-YAG
200 Hz
to 40 kDa 25 µm
100 µm
MassLynx, BioMap XML
MALDI micro MX Waters TOF N2
20 Hz
full 25 µm
200 µm
MassLynx, BioMap XML

(The use of a number of registered trademarks and tradenames throughout the site in referring to third-party products, vendors, or companies. These trademarks and tradenames are the property of the corresponding companies and the MALDI MS IG hereby acknowledges their ownership of such tradenames and trademarks.)

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